AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 258: E727-E736, 1990;
0193-1849/90 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jacquez, J. A.
Right arrow Articles by Perry, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jacquez, J. A.
Right arrow Articles by Perry, T.

AJP - Endocrinology and Metabolism, Vol 258, Issue 4 E727-E736, Copyright © 1990 by American Physiological Society

ARTICLES

Parameter estimation: local identifiability of parameters

J. A. Jacquez and T. Perry
Department of Physiology, University of Michigan, Ann Arbor 48109-0622.

For biological systems one often cannot set up experiments to measure all of the state variables. If only a subset of the state variables can be measured, it is possible that some of the system parameters cannot influence the measured state variables or that they do so in combinations that do not define the parameters' effects separately. Such parameters are unidentifiable and are in theory unestimable. Given a model of the system, linear or nonlinear, and initial estimates of the values of all parameters, we exhibit a simple theory and describe a program for checking the local identifiability of the parameters at the initial estimates for given experiments on the model. The program, IDENT, is available from the authors.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
D. J. Klinke II
An age-structured model of dendritic cell trafficking in the lung.
Am J Physiol Lung Cell Mol Physiol, November 1, 2006; 291(5): L1038 - L1049.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
W. Kang and M. Weiss
Digoxin Uptake, Receptor Heterogeneity, and Inotropic Response in the Isolated Rat Heart: A Comprehensive Kinetic Model
J. Pharmacol. Exp. Ther., August 1, 2002; 302(2): 577 - 583.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
L. V. Miller, N. F. Krebs, and K. M. Hambidge
Development of a compartmental model of human zinc metabolism: identifiability and multiple studies analyses
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2000; 279(5): R1671 - R1684.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. H. Audi, L. E. Olson, R. D. Bongard, D. L. Roerig, M. L. Schulte, and C. A. Dawson
Toluidine blue O and methylene blue as endothelial redox probes in the intact lung
Am J Physiol Heart Circ Physiol, January 1, 2000; 278(1): H137 - H150.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
T. C. Krejcie, T. K. Henthorn, W. B. Gentry, C. U. Niemann, C. Enders-Klein, C. A. Shanks, and M. J. Avram
Modifications of Blood Volume Alter the Disposition of Markers of Blood Volume, Extracellular Fluid, and Total Body Water
J. Pharmacol. Exp. Ther., December 1, 1999; 291(3): 1308 - 1316.
[Abstract] [Full Text]

Home page
 J. Appl. Physiol.Home page
S. H. Audi, C. A. Dawson, J. H. Linehan, G. S. Krenz, S. B. Ahlf, and D. L. Roerig
Pulmonary disposition of lipophilic amine compounds in the isolated perfused rabbit lung
J Appl Physiol, February 1, 1998; 84(2): 516 - 530.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online