AJP - Endo Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 232: E574-E579, 1977;
0193-1849/77 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Podesta, R.
Right arrow Articles by Mettrick, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Podesta, R.
Right arrow Articles by Mettrick, D.
AJP: Endocrinology and Metabolism, Vol 232, Issue 6, E574-E579
Copyright © 1977 by American Physiological Society

ARTICLES

HCO3- and H+ secretion in rat ileum in vivo

RB Podesta and DF Mettrick

Replacing Cl- in the perfusion fluids decreased the luminal pH of rat ileum perfused in vivo. Varying the initial pH in Cl- depletion studies indicated an equilibrium pH near 6.6. Na+ depletion in Cl- deleted fluids partially inhibited luminal acidification. Addition of HCO3- accelerated Na+ absorption and decreased Cl- absorption. Luminal PCO2 was increased using fluids buffered to initial pH 6.6, suggesting secretion of HCO3- rather than OH-. The decreased HCO3- secretion using Cl- depleted fluids was not due to an acclerated rate of H+ secretion. Reaffirmed and expanded in this study is an ileal H+ secretory process that is partially related to Na+ absorption and direct HCO3- secretion that is related to Cl- and Na+ absorption.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online